Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2007-09-11
2007-09-11
Foley, Shanon (Department: 1642)
Chemistry: molecular biology and microbiology
Vector, per se
C435S252300, C435S069100, C536S023100, C536S024500, C514S04400A
Reexamination Certificate
active
09047652
ABSTRACT:
The expression and subcellular localization of peripheral-type benzodiazepine receptors (PBR) is shown in this application to correlate with the metastatic potential of cells, and increased cell proliferation. Inhibition of PBR expression, function or stability results in a decrease in cell proliferation. Compositions and methods for regulating and/or monitoring PBR and its expression are useful for the detection, diagnosis, prognosis and treatment of solid tumors, in particular, breast cancer.
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Culty Martine
Papadopoulos Vassilios
Davis Minh-Tam
Foley Shanon
Georgetown University
Schwegman Lundberg Woessner & Kluth P.A.
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