Peripheral nerve regeneration

Details Peripheral nerve regeneration Peripheral nerve regeneration

1987-07-28

1988-07-26

Apley, Richard J.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

623 66, 128334R, A61F 202

Patent

active

047597640

ABSTRACT:
Basal lamina grafts for reconnecting severed nerves are prepared from muscle by removing cellular material therefrom while preserving the tubular structure of the basal lamina. When connected to nerve stumps the basal lamina surfaces promote axon regeneration therethrough, eventually reestablishing nerve function through the regenerated graft.

REFERENCES:
patent: 3551560 (1970-12-01), Thiele
patent: 4662884 (1987-05-01), Stensaas
Jewett & McCarrol; Nerve Repair & Regeneration Its Clinical & Experimental Basis; "Chapter 25"; 1979 pp. 235-243.
Wallis, I., Koenig, E. and Rose, S. (1980) Biochimica et Biophysica Acta, 599, 505-517.
Wallis, I. and Koenig, E. (1980) Biochimica et Biophysica Acta, 599, 518-527.
Keynes, R. J., Hopkins, W. G. and Huang, C. L. H. (1984) Brain Research, 295, 275-281.
Ide, C., (1984), Neuroscience Research, 1, 379-391.
R. Madison et al., "Increased Rate of Peripheral Nerve Regeneration Using Bioresorbable Nerve Guides and a Laminin-Containing Gel," Exp. Neurol 88, 767-772 (1985).

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