Periodontal toothpaste with wound-healing properties

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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424 49, 424 95, A61K 716, A61K 718

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active

045754578

ABSTRACT:
Pharmaceutical composition of skin respiratory factor (SRF), sodium chloride, bicarbonate, fluoride and zinc chloride in a suitable toothpaste vehicle provides effective therapy for gingivitis when brushed on the teeth and gingivae.
Pharmaceutical composition of SRF in a viscous composition suitable for application to the gingivae and effective over an extended period of time for healing tissue damaged by gingevitis. A toothpaste tube for packaging a pharmaceutical composition of SRF, sodium chloride, bicarbonate, fluoride and zinc chloride.

REFERENCES:
patent: 2239345 (1941-04-01), Sperti
patent: 2320478 (1943-06-01), Sperti
patent: 2320479 (1943-06-01), Sperti
patent: 2789731 (1957-04-01), Marrafino
patent: 4098435 (1978-07-01), Weyn
Cerra, M., et al., J. Periodontol. 53:599-603, Oct. 1982.
Stoller, N., et al., presented at the A.A.P. annual session, Research Forum, 1982.
Greenwell, H., et al., J.A.D.A. 106:457-461, Apr., 1983.
Wolff, L., et al., J. Dent. Res. 17:537-540, Sep., 1982.
West, T., et al., J. Periodontol. 54:339-346, Jun. 1983.

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