Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1980-04-24
1981-05-26
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 57, A61K 718
Patent
active
042698235
ABSTRACT:
A periodontal dental preparation is disclosed comprising folic acid, a dentally acceptable water-insoluble polishing agent which reduces the soluble folic acid present in the preparation and a fluorine-containing agent which increases retention of soluble folic acid in said preparation, the fluorine-containing agent comprising an alkali metal fluoride, and alkali metal monofluorophosphate, or a mixture thereof.
REFERENCES:
Slovokhotnova, Chem. Abstr. 71, #10826(d), (1969), Role of B-Vitamins in Preventing Dental Caries.
Vogel et al., Chem. Abstr. 86, #657455, (1977), The Effect of Folic Acid on Gingival Health.
Dreizen et al., J. Dent. Res., 49(3):616-620, May, Jun. 1970, The Effect of Folic Acid Deficiency on the Marmoset Oral Mucosa.
Abstr. In Chem. Abstr. 73, #106848e, (1970).
Koehler, Chem. Abstr. 80, #149035z, (1974), of Ger. Off. No. 2,342,553, Mar. 7, 1974.
Baines Eric
Harvey Kenneth
Colgate-Palmolive Co.
Grill M. M.
Rose Shep K.
Stone R. L.
Sylvester H. S.
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