Periodontal composition and method

Drug – bio-affecting and body treating compositions – Dentifrices – Oxygen or chlorine releasing compound containing

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424613, A61K 720, A61K 3340

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active

048972584

ABSTRACT:
A non-aqueous paste or gel dentifrice composition comprising a water soluble, non-aqueous vehicle having dispersed therein an orally acceptable inorganic peroxide and a bicarbonate salt. The quantities and relative proportions of the peroxide and bicarbonate are sufficient to provide quantities of bactericidally active oxygen upon breakdown of said peroxide when intermixing with water and introduction into the oral cavity. The bicarbonate also provides a neutral or basic pH upon dispersal and substantial dissolution of the composition in water. Preferably the composition comprises sodium bicarbonate and calcium peroxide in a preferable weight ratio (based on 60% CaO.sub.2 in the peroxide) of from about 4:1 to 6:1.

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