Periodontal composition and method

Drug – bio-affecting and body treating compositions – Dentifrices – Oxygen or chlorine releasing compound containing

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Details

424613, 424717, A61K 720, A61K 3340

Patent

active

048370088

ABSTRACT:
A non-aqueous paste or gel dentifrice composition comprising a water soluble, non-aqueous vehicle having dispersed therein an orally acceptable organic or inorganic peroxide and a bicarbonate salt. The quantities and relative proportions of the peroxide and bicarbonate are sufficient to provide quantities of bactericidally active oxygen upon breakdown of said peroxide by tissue contact and/or by reaction with said bicarbonate in the oral cavity. The bicarbonate also provides a neutral or basic pH upon dissolution of the composition in water. The peroxide and/or bicarbonate is provided with a water soluble barrier coating which is insoluble in the vehicle, to prevent reaction therebetween in the absence of water dissolution of the coating. Normal dentifrice adjuvants may also be present, which can similarly be provided with a water soluble barrier coating.

REFERENCES:
patent: 959605 (1910-05-01), Puelsser
patent: 1018240 (1912-02-01), Von Foregger
patent: 1863116 (1932-06-01), Heiman
patent: 2035267 (1936-03-01), Fleischmann
patent: 2052694 (1936-09-01), Breivogel
patent: 2054742 (1936-09-01), Elbel
patent: 2090437 (1937-08-01), Woldman
patent: 2218172 (1940-10-01), Kokatnor
patent: 3671629 (1972-06-01), Levy et al.
patent: 4487757 (1984-12-01), Kiozpeoplou
patent: 4528180 (1985-07-01), Schaeffer
patent: 4582701 (1986-04-01), Piechota
patent: 4647451 (1987-03-01), Piechota
patent: 4687663 (1987-08-01), Schaeffer
patent: 4776560 (1988-10-01), Ford
PDR (1982), Non-Prescription Drugs, "Glyoxide", Marion Labs., p. 561.

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