Perhydrothiazepine derivatives, their preparation and their ther

Details Perhydrothiazepine derivatives, their preparation and their ther Perhydrothiazepine derivatives, their preparation and their ther

1985-04-09

1987-10-13

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540488, C07D28106, A61K 3155

Patent

active

046999051

ABSTRACT:
Compounds of formula (I): ##STR1## (wherein: R.sup.1 represents an optionally substituted alkyl, cycloalkyl, aryl, partially hydrogenated aryl or heterocyclic group; R.sup.2, R.sup.3, R.sup.4 and R.sup.5 represent hydrogen or an optionally substituted alkyl, cycloalkyl, aralkyl, aryl, heterocyclic or heterocyclic-alkyl group or any adjacent pair thereof form a cyclic structure, at least one not being hydrogen; A represents a bond, or a methylene, ethylene, oxymethyl or thiomethyl group; B represents an alkylene, alkylidene, cycloalkylene or cycloalkylidene group; and n is 0, 1 or 2) and salts and esters thereof are hypotensive agents.

REFERENCES:
patent: 4587050 (1986-05-01), Harris et al.

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