Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Reexamination Certificate
2009-10-01
2011-11-22
Fronda, Christian (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
C435S183000, C435S252300, C536S023200
Reexamination Certificate
active
08062875
ABSTRACT:
Disclosed herein are variants enzymes that are structurally classified as CE-7 enzymes and have perhydrolysis activity. Also disclosed herein is a process for producing peroxycarboxylic acids from carboxylic acid esters using the aforementioned variant enzymes as well as methods and compositions comprising the variant enzymes. Further, disinfectant formulations comprising the peroxycarboxylic acids produced by the processes described herein are provided.
REFERENCES:
patent: 3974082 (1976-08-01), Weyn
patent: 4444886 (1984-04-01), Esders et al.
patent: 4585150 (1986-04-01), Beacham et al.
patent: 4678103 (1987-07-01), Dirksing
patent: 5108457 (1992-04-01), Poulose et al.
patent: 5116575 (1992-05-01), Badertscher et al.
patent: 5152461 (1992-10-01), Proctor
patent: 5281525 (1994-01-01), Mitsushima et al.
patent: 5296161 (1994-03-01), Wiersema et al.
patent: 5338676 (1994-08-01), Mitsushima et al.
patent: 5364554 (1994-11-01), Stanislowski et al.
patent: 5398846 (1995-03-01), Corba et al.
patent: 5528152 (1996-06-01), Hinoshita et al.
patent: 5532157 (1996-07-01), Fink
patent: 5605793 (1997-02-01), Stemmer
patent: 5624634 (1997-04-01), Brougham et al.
patent: 5683724 (1997-11-01), Hei et al.
patent: 5811238 (1998-09-01), Stemmer et al.
patent: 5830721 (1998-11-01), Stemmer et al.
patent: 5837458 (1998-11-01), Minshull et al.
patent: 5862949 (1999-01-01), Markey et al.
patent: 5932532 (1999-08-01), Ghosh et al.
patent: 5954213 (1999-09-01), Gerhart et al.
patent: 6183807 (2001-02-01), Gutzmann et al.
patent: 6210639 (2001-04-01), Vlass et al.
patent: 6223942 (2001-05-01), Markey et al.
patent: 6319888 (2001-11-01), Wei et al.
patent: 6391840 (2002-05-01), Thompson et al.
patent: 6465233 (2002-10-01), Knauseder et al.
patent: 6518307 (2003-02-01), McKenzie et al.
patent: 6545047 (2003-04-01), Gutzmann et al.
patent: 6635286 (2003-10-01), Hei et al.
patent: 6645233 (2003-11-01), Ayers et al.
patent: 6758411 (2004-07-01), Conway et al.
patent: 6995125 (2006-02-01), Dasque et al.
patent: 7384787 (2008-06-01), Kazlauskas et al.
patent: 7448556 (2008-11-01), Muehlhausen et al.
patent: 7550420 (2009-06-01), DiCosimo et al.
patent: 7612030 (2009-11-01), DiCosimo et al.
patent: 7723083 (2010-05-01), DiCosimo et al.
patent: 2002/0030063 (2002-03-01), Leray et al.
patent: 2004/0127381 (2004-07-01), Scialla et al.
patent: 2005/0008526 (2005-01-01), Bianchetti et al.
patent: 2008/0176299 (2008-07-01), Dicosimo et al.
patent: 2008/0176783 (2008-07-01), DiCosimo et al.
patent: 2009/0005590 (2009-01-01), DiCosimo et al.
patent: 2009/0305366 (2009-12-01), DiCosimo et al.
patent: 2009/0311763 (2009-12-01), DiCosimo et al.
patent: 2009/0312420 (2009-12-01), DiCosimo et al.
patent: 2009/0325266 (2009-12-01), DiCosimo et al.
patent: 2010/0041752 (2010-02-01), DiCosimo et al.
patent: 2010/0136639 (2010-06-01), DiCosimo et al.
patent: 2010/0152292 (2010-06-01), DiCosimo et al.
patent: 2010/0168234 (2010-07-01), DiCosimo et al.
patent: 2010/0168235 (2010-07-01), DiCosimo et al.
patent: 2010/0168236 (2010-07-01), DiCosimo et al.
patent: 2010/0168237 (2010-07-01), DiCosimo et al.
patent: 101326288 (2008-12-01), None
patent: 101558161 (2009-10-01), None
patent: 0807156 (1997-11-01), None
patent: 2121951 (2009-11-01), None
patent: 1960529 (2010-02-01), None
patent: WO96/32149 (1996-10-01), None
patent: WO97/41833 (1997-11-01), None
patent: WO99/03984 (1999-01-01), None
patent: WO00/61713 (2000-10-01), None
patent: WO02/22467 (2002-03-01), None
patent: WO 2004/058961 (2004-07-01), None
patent: WO2005/035705 (2005-04-01), None
patent: WO 2006/119060 (2006-11-01), None
patent: WO2007/070609 (2007-06-01), None
patent: WO2007/106293 (2007-09-01), None
patent: WO 2008/073139 (2008-06-01), None
patent: WO2008/073139 (2008-06-01), None
patent: WO 2009/067279 (2009-05-01), None
Chica et al. Curr Opin Biotechnol. Aug. 2005;16(4):378-84.
Sen et al. Appl Biochem Biotechnol. Dec. 2007;143(3):212-23.
Accession Q9WXT2. Published Nov. 1, 1999.
Justus Liebigs Annalen der Chemie; 105:206 (1858).
Wurtz, Annales de Chimie; 55:443 (1859).
Seelig, Univ. of Berlin Laboratory; 24: 3466 (1891).
Stöchiometrie und Verwandtschaftslehre vol. 183, [K. Loskit, On the Knowledge of Triglycerides, p. 135-155], vol. 134, Nos. 1 and 2, May 1928.
Abbottet al., Physical Properties and Kinetic Behavior of a Cephalosporin . . . , Appl. Microbiol. 30(3):413-419 (1975).
Funasaki, N. et al., Intramolecular Hydrophobic Association of Two Alkyl Chains of Ollgoethylene Glycol Diethers and Diesters in Water, J. Phys. Chem. 88:5786-5790 (1984).
C. Laane et al., Rules for Optimization of Biocatalysis in Organic Solvents, Biotechnol. Bioeng. 30:81-87 (1987).
Cowan et al., Biocatalysis in Organic Phase Media., Ch. 7 in Biocatalysis at Extreme Temperatures . . . , Amer. Chem. Soc. Symposium Series 498, pp. 86-107 (1992).
Lee, Y.E. et al., Genetic Organization, Sequence and Biochemical Characterization of Recombinant . . . , J Gen Microbiol. (1993), 139:1235-1243.
Mitsushima et al Gene Cloning, Nucleotide Sequence, and Expression . . . , Appl. Env. Microbiol. 61(6):2224-2229, (1995).
Fromant et al., Direct Random Mutagenesis of Gene-Sized DNA Fragments Using Polymerase Chain Reaction, Analytical Biochemistry 224, 347-353(1995).
Kobayashi et al., Purification and Properties of an Alkaline Protease fromAlkalophilic bacillussp. KSM-K16, Appl. Microbiol. Biotechnol. 43 (3), 473-481 (1995).
Kuo, S-J. et al., Solvent Polarity Influences Product Selectivity of Lipase-Mediated Esterification Reactions in Microaqueous Media, J. Am. Oil Chem. Soc. 73:1427-1433 (1996).
Pinkernell, U. et al., Simultaneous HPLC Determination of Peroxyacetic Acid and Hydrogen Peroxide, Anal. Chem., 69(17)3623-3627 (1997).
Kunst et al , The Complete Genome Sequence of the Gram-Positive BacteriumBacillus subtilis, Nature 390:249-256 (1997).
Lin-Goerke et al., PCR-based Random Mutagenesis Using Manganese and Reduced dNTP Concentration, Biotechniques, 23(3):409-12 (1997).
Nixon et al., Assembly of an Active Enzyme by the Linkage of Two Protein Modules, PNAS, 94:1069-1073 (1997).
Lorenz et al., Isolation, Analysis and Expresion of Two Genes from Thermoanaerobacterium . . . , J. Bacteriol 179:5436-5441 (1997).
Politino et al., Purification and Characterization of a Cephalosporin Esterase . . . , Appl. Environ. Microbiol., 63(12):4807-4811 (1997).
Sakai et al., Purification and Properties of Cephalosporing-C Deacetylase from the Yeast . . . , J. Ferment. Bioeng. 85:53-57 (1998).
Gilbert et al., Recent Advances in Carbohydrate Bioengineering, The Royal Society of Chemistry, Cambridge, pp. 3-12. (1999).
Nelson et al., Evidence for Lateral Gene Transfer Between Archaea and Bacteria From Genome Sequence of Thermotoga Maritime, Nature, 399:323-329 (1999).
Melnikov et al., Random Mutagenesis by Recombinational Capture of PCR Products inBacillus subtilisandAcinetobacter calcoaceticus, Nucleic Acids Res. 27(4):1056-62 (1999).
Cardoza et al., A Cephalosporin C Acetylhydrolase is Present in the Cultures ofNocardia lactamdurans, Appl. Microbiol. Biotechnol., 54(3):406-412 (2000).
Berman, H.M. et al., The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000).
Degrassi et al., The Acetyl Xyland Esterase ofBacillus pumilusBelongs to a Family . . . , Microbiology., 146:1585-1591 (2000).
Takami et al., Complete Genome Sequences of the Alkaliphilic BacteriumBacillus haloduransand . . . , NAR, 28(21):4317-4331 (2000).
Gunning, Y. M. et al., Phase Behavior and Component Partitioning in Low Water Content Amorphous Carbohydrates . . . , J. Agric. Food Chem. 48:395-399 (2000).
Vincent et al., Multifunctional Xylooligosaccharide/Cephalosporin C Deacetylase . . . , J. Mol. Biol., 330:593-606 (2003).
Ru et al, On the Salt-Induced Activation of Lyophilized Enzyme in Organic Solvents, J. Am. Chem. Soc. vol. 122, No, 8, pp. 1465-1571, Feb. 9, 2000.
Ikeda et al., Complete Genome Sequence and Comparative Analysis of the Industrial Microorganism Streptomyces Avermitilis, Nat. Biotechnol. 21 (5), 526-531 (2003).
H.M. Berman, Announcing the Worldwide Protein Data Bank, Nature Structural Biology 10 (12), p. 980 (2
DiCosimo Robert
Payne Mark S.
Yin Tyler
E. I. du Pont de Nemous & Company
Fronda Christian
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