Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1974-02-28
1978-09-12
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
260576, 260577, 544154, 544155, 544381, 544358, 560103, 560121, 560123, 560128, 560220, 560256, 544360, 544372, 2602433, 26029356, 26029362, 26032633, 2603265C, 2603268, 26032685, 260553D, 260558R, 260561R, 260561B, 260561HL, 260563P, 2605705CA, 2605709, C07D29502, C07D29508, C07D29514
Patent
active
041137264
ABSTRACT:
Compounds are provided having the structure ##STR1## wherein n is 1 or 2, n.sup.1 is 0, 1 or 2 and n.sup.2 is 0, 1, 2 or 3, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 may be the same or different and can be hydrogen, lower alkyl, halolower alkyl, acyl, lower alkoxy-carbonyl ##STR2## amido ##STR3## or lower alkoxyalkylene, R can be lower alkoxy, lower alkyl or cycloalkyl, R.sub.8 can be hydrogen, lower alkyl, cycloalkyl, hydroxy, dialkylaminoalkyl or R.sub.9 O(CH.sub.2)q-. X is a single bond or a straight or branched bivalent aliphatic radical and Y is ##STR4## These compounds are useful in the treatment of hypertension.
REFERENCES:
patent: 3751420 (1973-08-01), Hauck et al.
Cimarusti Christopher Michael
Hauck Frederic Peter
Barrack Donald J.
E. R. Squibb & Sons Inc.
Jiles Henry R.
Levinson Lawrence S.
Schwartz Richard A.
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