Perhydrofluorenetetrol and perhydrophenanthrenetetrol derivative

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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260576, 260577, 544154, 544155, 544381, 544358, 560103, 560121, 560123, 560128, 560220, 560256, 544360, 544372, 2602433, 26029356, 26029362, 26032633, 2603265C, 2603268, 26032685, 260553D, 260558R, 260561R, 260561B, 260561HL, 260563P, 2605705CA, 2605709, C07D29502, C07D29508, C07D29514

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active

041137264

ABSTRACT:
Compounds are provided having the structure ##STR1## wherein n is 1 or 2, n.sup.1 is 0, 1 or 2 and n.sup.2 is 0, 1, 2 or 3, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 may be the same or different and can be hydrogen, lower alkyl, halolower alkyl, acyl, lower alkoxy-carbonyl ##STR2## amido ##STR3## or lower alkoxyalkylene, R can be lower alkoxy, lower alkyl or cycloalkyl, R.sub.8 can be hydrogen, lower alkyl, cycloalkyl, hydroxy, dialkylaminoalkyl or R.sub.9 O(CH.sub.2)q-. X is a single bond or a straight or branched bivalent aliphatic radical and Y is ##STR4## These compounds are useful in the treatment of hypertension.

REFERENCES:
patent: 3751420 (1973-08-01), Hauck et al.

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