Perfusion system for organ preservation

Refrigeration – Material cooling means including gas-liquid contactor – Means feeding gas into pressurized receiver

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128 1R, 435 1, B01F 304, A61B 1900

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active

041865650

ABSTRACT:
A portable perfusion system for organ preservation comprising a cart on which a refrigeration unit, a pump unit and a cassette are mounted with the pump and cassette being removable for separate transport. The cassette includes an organ receptacle, a heat exchanger, a membrane oxygenator, a bubble trap and an ice deposit area. The heat exchanger is connected to the refrigeration unit and the perfusate is pumped by a non-pulsatile pump through the heat exchanger to the bubble trap and, in turn, to the organ. An oxygen supply on the cart supplies oxygen to the membrane oxygenator which functions to oxygenate the perfusate.

REFERENCES:
patent: 3406531 (1968-10-01), Swenson et al.
patent: 3545221 (1970-09-01), Swenson et al.
patent: 3607646 (1971-09-01), de Roissart
patent: 3753865 (1973-08-01), Belzer et al.
patent: 3777507 (1973-12-01), Burton et al.
patent: 3914954 (1975-10-01), Doerig
patent: 3995444 (1976-12-01), Clark et al.
"Clinical Kidney Preservation With & Without Continuous Perfusion", by Claes, Blohme & Gelin-published in EDTA Bulletin Jul. 1971.
"Transportable Organ-Perfusion System for Kidney Preservation" by Moberg et al., in The Lancet, Dec. 25, 1971.

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