Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Reexamination Certificate
2004-05-12
2008-12-16
Tate, Christopher R. (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
Reexamination Certificate
active
07465558
ABSTRACT:
A system and method for high throughput patch clamp measurements to study the effect of various chemicals on ion transfer channels is provided. One or more patch clamp configurations is established, each comprising a cell sealed to a pipette. The pipettes are affixed to a pipette fixture. The pipette fixture and a plate comprising one or more wells are relatively moved so that each cell is inside a well. Electrical properties of the cells are measured.
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E. Neher et al., The extracellular patch clamp: a method for resolving currents through individual open channels in biological membranes, Pflugers Arch 375, 219-228 (1978).
Bowlby Mark Robert
Federkiewicz Anton
Merrill Thomas L.
Vasylyev Dmytro Vasylyovych
Hunton & Williams LLP
Tate Christopher R.
Wood Amanda P
Wyeth
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