Surgery – Radioactive substance applied to body for therapy – Radioactive substance placed within body
Patent
1997-03-06
2000-08-08
Lacyk, John P.
Surgery
Radioactive substance applied to body for therapy
Radioactive substance placed within body
A61N 500
Patent
active
060994541
ABSTRACT:
A catheter capable of irradiating blood vessel walls to inhibit restenosis after angioplasty. Catheters are capable of simultaneous irradiation and angioplasty. Preferred catheters include a helical perfusion balloon having closely spaced or contacting adjacent windings when inflated. A helical balloon with strand windings having little space therebetween decreases the amount of blood between the balloon exterior surface and vessel walls. A removable, sheathed, elongate radiation source is used with some embodiments. A fixed, flexible sheath partitioning the catheter lumen into sterile and non-sterile portions is included in another embodiment. Internal rather than external perfusion and use of gas to inflate the balloon decrease the absorption of beta radiation by blood, and liquid inflation fluid, respectively.
REFERENCES:
patent: 2546761 (1951-03-01), Loftus
patent: 2862108 (1958-11-01), Meilink
patent: 2955208 (1960-10-01), Stevens
patent: 3060924 (1962-10-01), Rush
patent: 3147383 (1964-09-01), Prest
patent: 3324847 (1967-06-01), Zoumboulis
patent: 3505991 (1970-04-01), Hellerstein et al.
patent: 3643096 (1972-02-01), Jeffries, Jr. et al.
patent: 3669093 (1972-06-01), Sauerwein et al.
patent: 3750653 (1973-08-01), Simon
patent: 3811426 (1974-05-01), Culver et al.
patent: 3861380 (1975-01-01), Chassagne et al.
patent: 3866050 (1975-02-01), Whitfield
patent: 3927325 (1975-12-01), Hungate et al.
patent: 4096862 (1978-06-01), DeLuca
patent: 4220864 (1980-09-01), Sauerwein et al.
patent: 4225790 (1980-09-01), Parsons, Jr. et al.
patent: 4244357 (1981-01-01), Morrison
patent: 4281252 (1981-07-01), Parsons, Jr. et al.
patent: 4314157 (1982-02-01), Gaines
patent: 4364376 (1982-12-01), Bigham
patent: 4584991 (1986-04-01), Tokita et al.
patent: 4588395 (1986-05-01), Lemelson
patent: 4631415 (1986-12-01), Sauerwein et al.
patent: 4702228 (1987-10-01), Russell, Jr. et al.
patent: 4706652 (1987-11-01), Horowitz
patent: 4763642 (1988-08-01), Horowitz
patent: 4763671 (1988-08-01), Goffinet
patent: 4782834 (1988-11-01), Maguire et al.
patent: 4784116 (1988-11-01), Russell, Jr. et al.
patent: 4799479 (1989-01-01), Spears
patent: 4815449 (1989-03-01), Horowitz
patent: 4819618 (1989-04-01), Liprie
patent: 4851694 (1989-07-01), Rague et al.
patent: 4861520 (1989-08-01), van't Hooft et al.
patent: 4881937 (1989-11-01), van't Hooft et al.
patent: 4897076 (1990-01-01), Puthawala et al.
patent: 4936823 (1990-06-01), Colvin et al.
patent: 4963128 (1990-10-01), Daniel et al.
patent: 4969863 (1990-11-01), van't Hooft et al.
patent: 4976266 (1990-12-01), Huffman et al.
patent: 4976680 (1990-12-01), Hayman et al.
patent: 4976690 (1990-12-01), Solar et al.
patent: 5030194 (1991-07-01), Van't Hooft
patent: 5032113 (1991-07-01), Burns
patent: 5059166 (1991-10-01), Fischell et al.
patent: 5084001 (1992-01-01), Van't Hooft et al.
patent: 5084002 (1992-01-01), Liprie
patent: 5092834 (1992-03-01), Bradshaw et al.
patent: 5103395 (1992-04-01), Spako et al.
patent: 5106360 (1992-04-01), Ishiwara et al.
patent: 5120973 (1992-06-01), Rohe et al.
patent: 5139473 (1992-08-01), Bradshaw et al.
patent: 5141487 (1992-08-01), Liprie
patent: 5147282 (1992-09-01), Kan
patent: 5163896 (1992-11-01), Suthanthiran et al.
patent: 5176617 (1993-01-01), Fischell et al.
patent: 5183455 (1993-02-01), Hayman et al.
patent: 5199939 (1993-04-01), Dake et al.
patent: 5213561 (1993-05-01), Weinstein et al.
patent: 5267960 (1993-12-01), Hayman et al.
patent: 5282781 (1994-02-01), Liprie
patent: 5302168 (1994-04-01), Hess
patent: 5308356 (1994-05-01), Blackshear, Jr. et al.
patent: 5344383 (1994-09-01), Liping
patent: 5354257 (1994-10-01), Roubin et al.
patent: 5370685 (1994-12-01), Stevens
patent: 5391139 (1995-02-01), Edmundson
patent: 5405309 (1995-04-01), Carden, Jr.
patent: 5409015 (1995-04-01), Palermo
patent: 5411466 (1995-05-01), Hess
patent: 5417653 (1995-05-01), Sahota et al.
patent: 5425720 (1995-06-01), Rogalsky et al.
patent: 5429582 (1995-07-01), Williams
patent: 5484384 (1996-01-01), Fearnot
patent: 5498227 (1996-03-01), Mawad
patent: 5503613 (1996-04-01), Weinberger
patent: 5503614 (1996-04-01), Liprie
patent: 5532122 (1996-07-01), Drukier
patent: 5538494 (1996-07-01), Matsuda
patent: 5540659 (1996-07-01), Teirstein
patent: 5545132 (1996-08-01), Fagan et al.
patent: 5556389 (1996-09-01), Liprie
patent: 5575749 (1996-11-01), Liprie
patent: 5605530 (1997-02-01), Fischell et al.
patent: 5611767 (1997-03-01), Williams
patent: 5616114 (1997-04-01), Thornton et al.
patent: 5618266 (1997-04-01), Liprie
patent: 5624372 (1997-04-01), Liprie
patent: 5643171 (1997-07-01), Bradshaw et al.
patent: 5649924 (1997-07-01), Everett et al.
patent: 5653683 (1997-08-01), D'Andrea
patent: 5662580 (1997-09-01), Bradshaw et al.
patent: 5674177 (1997-10-01), Hehrlein et al.
patent: 5683345 (1997-11-01), Waksman et al.
patent: 5688220 (1997-11-01), Verin et al.
patent: 5707332 (1998-01-01), Weinberger
patent: 5720717 (1998-02-01), D'Andrea
patent: 5722984 (1998-03-01), Fischell et al.
patent: 5728042 (1998-03-01), Schwager
patent: 5730698 (1998-03-01), Fischell et al.
patent: 5782740 (1998-07-01), Schneiderman
patent: 5782742 (1998-07-01), Crocker et al.
patent: 5795286 (1998-08-01), Fischell et al.
patent: 5800333 (1998-09-01), Liprie
patent: 5803895 (1998-09-01), Kronholz et al.
patent: 5807231 (1998-09-01), Liprie
patent: 5816259 (1998-10-01), Rose
patent: 5816999 (1998-10-01), Bischoff et al.
patent: 5820553 (1998-10-01), Hughes
patent: 5833593 (1998-11-01), Liprie
patent: 5840008 (1998-11-01), Klein et al.
patent: 5840009 (1998-11-01), Fischell et al.
patent: 5840064 (1998-11-01), Liprie
patent: 5843163 (1998-12-01), Wall
patent: 5851171 (1998-12-01), Gasson
patent: 5851172 (1998-12-01), Bueche et al.
patent: 5855546 (1999-01-01), Hastings et al.
patent: 5857956 (1999-01-01), Liprie
patent: 5863284 (1999-01-01), Klein
patent: 5863285 (1999-01-01), Coletti
patent: 5865720 (1999-02-01), Hastings et al.
patent: 5871436 (1999-02-01), Eury
patent: 5871437 (1999-02-01), Alt
patent: 5873811 (1999-02-01), Wang et al.
patent: 5879282 (1999-03-01), Fischell et al.
patent: 5882290 (1999-03-01), Kume
patent: 5882291 (1999-03-01), Bradshaw et al.
patent: 5891091 (1999-04-01), Teirstein
patent: 5897573 (1999-04-01), Rosenthal et al.
patent: 5899882 (1999-05-01), Waksman et al.
Sutherland, "Managing Cancer Through Synergy", Administrative Radiology Journal, Nov. 1996, pp. 21-27.
Radiotherapy of Intraocular and Orbital Tumors, Springer-Verlak publisher, Berlin Heidelberg and New York, copyright 1993, pp. 23-30 and 363-367.
Tjho-Heslinga et al., "Results of ruthenium, irradiation of uveal melanoma", Radiotherapy Oncology, vol. 29, pp. 33-38, 1993.
Lommatzsch et al., "Radiation effects on the optic nerve observed after brachytherapy of choroidal melanomas with 106Ru/106Rh plaques", Graefe's Arch. Clin. Exp. Ophthalmology, vol. 232, pp. 482-487, 1994.
Raloff, "Nuclear Medicine Gets Friendlier -Experimental Therapies Seek to Poison Just the Disease", Science News, vol. 152, Jul. 19, 1997, pp. 40-41.
Fackelman, "Harbinger of a Heart Attack -Does a Protein in the Blood Foretell Heart Trouble", Science News, vol. 151, Jun. 14, 1997, pp. 374-375.
"Aids and Cancer Cured by Hyper-Oxygenation", Now What, Issue No. 1, Waves Forest, Monterey, California.
Li et al., "Reactive Oxygen Species Induce Apoptosis of Vascular Smooth Muscle Cell", FEBS Letters, 404, 1997, pp. 249-252.
Kalli, "Oxygen Emulsion The Question of Free Radicals", Internet Address http://www.livelinks.com/sumeria/oxy/rad2.html, Aug. 1, 1997.
Barry, "Reactive oxygen Species in Living Systems -Source: Biochemistry, and Role in Human Disease", Internet Address http:/www.livelinks.com/sumeria/oxy/reactive.html, Jul. 21, 1997 from American Journal of Medicine, vol. 91, No. 3c, Sep. 30, 1991, p. 14s(9).
Block, "Peroxygen Compounds, Chapter 9", Disinfection, Sterilization, and Preservation, Fourth Edition, Lea & Febiger, Philadelphia, Copyright 1991.
Moore, "Free Radial Generation by Thyroid Peroxidase and Its Effects on Cells in Vitro", phD. Dissertation, Group in Endocrinology-University of California, Be
Hastings Roger N.
Urick Michael J.
Lacyk John P.
Sci-Med Life Systems, Inc.
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