Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ether doai
Patent
1984-02-22
1990-07-24
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ether doai
564496, 564510, 568604, 568615, 568677, 568683, A61K 3108, C07C 4312
Patent
active
049435957
ABSTRACT:
There is provided a novel perfluorochemical represented by the formula, ##STR1## wherein R.sub.F is a perfluoroalkyl group, a perfluoro alkoxyalkyl group or a perfluoroalkyloxy group, X and X' are same as or different from each other and are a fluorine atom or a perfluoroalkyl group, and Y is a perfluoroalkyloxy group or a perfluoro dialkylamino group, the total number of the carbon atoms contained being an integer of 8 to 11 inclusive. The perfluorochemical is prepared by perfluorinating the corresponding partially fluorinated compound which may have unsaturated hydrocarbon moiety, only with molecular fluorine in a stoichiometric excess amount in an inert solvent.
The perfluorochemical is used for preparing a stable emulsion as blood substitutes or perfusion media.
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Ivanova et al., Chemical Abstracts, vol. 92, May 19, 1980, CA92:169098y, "Biological Properties of Emulsions of Some Organofluorine Compounds as Models of Blood Substitute-Oxygen Carriers".
Naito, deceased Ryoichi
Scherer, Jr. Kirby V.
Yamanouchi Kouichi
Yokoyama Kazumasa
O'Sullivan Peter G.
Raymond Richard L.
The Green Cross Corporation
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