Perfluorochemical emulsion artificial blood

Details Perfluorochemical emulsion artificial blood Perfluorochemical emulsion artificial blood

1982-07-27

1983-12-27

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424350, 424352, 424365, A61K 3113, A61K 31025

Patent

active

044230770

ABSTRACT:
Particles of perfluoro compound with a lipid coating are emulsified in aqueous medium, wherein the proportion of perfluoro compound in the emulsion is preferably about 30-75% (w/v) and the proportion of lipid is preferably about 7-9% (w/v). In the resulting stable emulsion 95% of these particles having diameters less than 0.2.mu.. The emulsion is useful as an artificial blood for transport and delivery of oxygen to body tissues.

REFERENCES:
patent: 3958014 (1976-05-01), Watanabe et al.
patent: 3962439 (1976-06-01), Yokoyama et al.
patent: 4133874 (1979-01-01), Miller et al.
patent: 4252827 (1981-02-01), Yokoyama et al.
Green Cross Corporation, "Technical Information Ser. No. 1", dated May 15, 1975, pp. 38-39.

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