Perfluoroalkylnaphthalene compounds

Details Perfluoroalkylnaphthalene compounds Perfluoroalkylnaphthalene compounds

1985-12-12

1987-10-13

Torrence, Dolph H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitriles

558424, 558425, C07C12162

Patent

active

046999930

ABSTRACT:
Novel compounds having greatest interest as biologically-active materials for the treatment of diabetic complications in mammals, or intermediates for such materials, are perfluoroalkyl compounds corresponding to the formula: ##STR1## wherein R and R' are independently selected from chloro, fluoro, nitro, hydroxy, and alkyl and alkoxy substituents containing 1-6 carbons; Q is --CN, --COOL, --COX, or --CTN(R")CH.sub.2 COOL; L is hydrogen, alkali metal, or saturated hydrocarbyl; X is halo; T is oxygen or sulfur; R" is an alkyl group containing 1-6 carbons; m is 0 or 1; and n is an integer of at least one.

REFERENCES:
patent: 3408411 (1968-10-01), Conrad et al.
patent: 4439617 (1984-03-01), Sestanj et al.
patent: 4590010 (1986-05-01), Ramachandran et al.
patent: 4604406 (1986-08-01), Bellini et al.
McLoughlin et al., Tetrahedron, vol. 25, pp. 5921-5940 (1969).
Kobayashi et al., Tetrahedron Letters, pp. 4071-4072 (1979).
Gassman et al., Tetrahedron Letters, vol. 26, No. 43, pp. 5243-5246 (1985).

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