Perfluoroalkyl-substituted, benzoylguanidines, a process for the

Details Perfluoroalkyl-substituted, benzoylguanidines, a process for the Perfluoroalkyl-substituted, benzoylguanidines, a process for the

1995-05-11

1996-11-05

Kumar, Shailendra

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514519, 514520, 514521, 514522, 558412, 558413, 558414, 558415, 564162, 564235, A61K 31165, C07C32323

Patent

active

055718426

ABSTRACT:
Perfluoroalkyl-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament containing them
A description is given of perfluoroalkyl-substituted benzoylguanidines of the formula I ##STR1## where R(1) is (C.sub.1 -C.sub.6)-perfluoroalkyl-SO.sub.m ; R(2) and R(3) are H, halogen, alk(yl)(oxy), phenoxy; R(4) and R(5) are H, alkyl, Hal, CN, OR(7), NR(8)R(9), --(CH.sub.2).sub.n --(CF.sub.2).sub.o --CF.sub.3 and of the pharmacologically acceptable salts thereof; the compounds I are obtained by reacting a compound II ##STR2## with guanidine, L being a leaving group which is able readily to undergo nucleophilic substitution.

REFERENCES:
patent: 3780027 (1973-12-01), Cragoe, Jr. et al.
patent: 5091394 (1992-02-01), Englert et al.
patent: 5373024 (1994-12-01), Lang et al.

Affiliated with

Also associated with

Rating

Perfluoroalkyl-substituted, benzoylguanidines, a process for the does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Perfluoroalkyl-substituted, benzoylguanidines, a process for the, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Perfluoroalkyl-substituted, benzoylguanidines, a process for the will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2015478