Perfluoro-crown ethers in fluorine magnetic resonance spectrosco

Details Perfluoro-crown ethers in fluorine magnetic resonance spectrosco Perfluoro-crown ethers in fluorine magnetic resonance spectrosco

1991-07-03

1993-03-23

Hollrah, Glennon H.

Chemistry: analytical and immunological testing

Nuclear magnetic resonance, electron spin resonance or other...

424 9, 1286534, 514450, 514832, G01N 2400, G01N 3100, A61K 31335

Patent

active

051963485

ABSTRACT:
A method is disclosed for nuclear magnetic resonance spectroscopy wherein the improvement is the use of perfluoro 15-crown-5 ether which has 20 magnetically similar fluorine providing a superior signal to noise ratio with resultant enhanced diagnostic resolution.

REFERENCES:
patent: 4523039 (1985-06-01), Lagow et al.
patent: 4570004 (1986-02-01), Lagow et al.
patent: 4639364 (1987-01-01), Hoey
patent: 4838274 (1939-06-01), Schweighardt et al.
patent: 5068098 (1991-11-01), Schweighardt et al.
patent: 5070213 (1991-12-01), Huang et al.
Bottomley, Pa., Computerized Radiology 8(2):57-77 (1984).
Nature, vol. 242, pp. 190-191, 1973 Lauterbur, PC.
Damadian, Science, vol. 171, p. 1151, 1971 Tumor Detection by Nuclear Magnetic Resonance.
Mattrey, R. F.; "Perfluorocarbon Compounds:Applications in Diagnostic Imaging"; SPIE; vol. 626, Medicine, XIV/Pacs IV (1986), pp. 18-23.
Longmaid, III et al.; "In vivo .sup.19 F NMR Imaging of Liver, Tumor and Abscess in Rats"; Investigative Radiology; Mar./Apr. 1985; vol. 20; pp. 141-144.
Patronas et al; "Brain-tumor Imaging Using Radiopaque Perfluorocarbon"; Journal of Neurosurgery; May 1983; vol. 58; pp. 650-653.
Mattrey, R. F. et al; "Perfluorochemicals as US Contrast Agents for Tumor Imaging and Hepatosplenography:Preliminary Clinical Results"; Radiology; May 1987; vol. 163; No. 2. pp. 339-343.
Parhami & Fung; "Fluorine-19 Relaxation Study of Perfluoro Chemicals as Oxygen Carriers"; J. Physical Chemicals; 1983; pp. 1928-1931.
Nunnally, et al; "Fluonine-19 (.sup.19 F) NMR in Vivo:Potential for Flow and Perfusion Measurements"; Proceedings of the Society and Magnetic Resonance in Medicine; 2nd Annual Meet.; Aug. 16-19; pp. 226.
Reid, et al; "The Influence of Oxygenation on the .sup.19 F Relaxation Rates in Flusol-da"; Phys. Med. Biol; vol. 30; No. 7; pp. 677-686 (1985).
Wyrwics et al; "Observations of Fluorinated Anesthetics in Rabbit Brain by .sup.19 F NMR"; Proceedings of the Soc. of Magnetic Resonance in Med; 2nd Annual Meet; Aug. 16-19; (1983); pp. 381-382.
Clark et al; "Perfluorinated Organic Liquids and Emulsions as Biocompatible NMR Imaging Agents for .sup.19 F and Dissolved Oxygen"; Adv. Exp. Med. Biol.; vol. 180(6); pp. 835-845; 1984.

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