Perfluoro compound dispersions containing reduced amounts of sur

Details Perfluoro compound dispersions containing reduced amounts of sur Perfluoro compound dispersions containing reduced amounts of sur

1986-10-03

1990-04-17

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

514755, 514756, 514832, A61K 3174, A61K 31025

Patent

active

049179306

ABSTRACT:
Compositions having enhanced gas and drug transporting capability, are prepared by providing a perfluoro compound dispersed in an aqueous medium with a surfactant to form an aqueous initial dispersion, concentrating the perfluoro compound phase of the dispersion as by centrifugation or filtration, wherein a portion of the surfactant remains complexed with the particles of the perfluoro compound phase and the balance of the surfactant is in the aqueous phase, separating the phases, and redispersing the particles of the concentrated perfluoro compound phase to form a final dispersion in which greater than 65% by weight, and preferably at least 75%, of the surfactant present is complexed with the perfluoro compound particles.

REFERENCES:
patent: 3547995 (1970-12-01), Bartlett
patent: 3778381 (1973-12-01), Rosano et al.
patent: 3828085 (1974-08-01), Price et al.
patent: 3911138 (1975-10-01), Clark
patent: 3993581 (1976-11-01), Yokoyama et al.
patent: 4105798 (1978-08-01), Moore et al.
patent: 4443480 (1984-04-01), Clark
patent: 4461717 (1984-07-01), Moore
Clark, Biomedical Aspects of Fluorine Chem., ed. Fuller et al.; Elsevier Biomedical Press, 1982.
Yokoyama et al., Biochemical Aspects of Fluorine Chemistry, ed. Fuller et al.; Elsevier Press, 1982.

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