Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1983-01-24
1985-12-31
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514832, 514833, 2602457, C07D49900, A61K 3140
Patent
active
045621837
ABSTRACT:
Novel perfluorinated heterocyclic compounds have an azabicyclodecane structure with fused 5- and 7-membered rings incorporating a bridgehead nitrogen atom. They are prepared by cobalt (III) fluoride fluorination of quinolines or alkyl quinolines and are useful, when emulsified in aqueous media, as blood substitutes or organ perfusates, prior to transplant.
REFERENCES:
patent: 3674785 (1972-07-01), Mitsch
patent: 4186253 (1980-01-01), Yokoyama et al.
patent: 4425347 (1984-01-01), Yokoyama et al.
patent: 4526969 (1985-07-01), Yokoyama et al.
Plevey et al., Journal of Fluorine Chemistry, 21 (1982) pp. 413-428, CA 197016, vol. 98 (1983).
Plevey Raymond G.
Sargent Colin R.
Tatlow John C.
Wotton David E. M.
Daus Donald G.
I.S.C. Chemicals Limited
Teoli, Jr. William A.
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