Surgery – Instruments – Cutting – puncturing or piercing
Patent
1998-11-02
2000-04-04
Buiz, Michael
Surgery
Instruments
Cutting, puncturing or piercing
128898, A61B 1732
Patent
active
060455659
ABSTRACT:
Devices and methods for increasing blood perfusion within the myocardium of the heart by wounding the myocardium and applying growth factors to promote vascularization. One method includes driving spikes into the myocardium from within the heart, with the spikes being formed of biodegradable material, containing releasable growth factors, and having lumens and side holes. An alternative method utilizes non-biodegradable spikes with lumens and side holes. Another method promotes vascularization by injecting angiogenic material into holes bored into the myocardium, leaving a patent hole. Another method includes injecting angiogenic material into the myocardium without boring, leaving no patent hole. The angiogenic material can be carried in a biodegradable adhesive. Revascularization of the myocardium is promoted in one method by externally wounding the heart and applying a patch including growth factors.
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Ellis Louis
Harrison Kent D.
Hendrickson Gary L.
Mickley Timothy J.
Wang Lixiao
Buiz Michael
Sci-Med Life Systems, Inc.
Truong Kevin
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