Percutaneous methods for creating native tissue venous valves

Surgery – Instruments – Blood vessel – duct or teat cutter – scrapper or abrader

Reexamination Certificate

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C606S194000

Reexamination Certificate

active

07955346

ABSTRACT:
Percutaneous methods of forming a venous valve from autologous tissue are disclosed. The methods include percutaneously creating one or two subintimal dissections for forming one or two flaps of intimal tissue. In one method, a puncture element is delivered by a catheter based delivery system to a treatment site where a new venous valve is to be created. The puncture element is deployed to gain access to a subintimal layer of the vein wall. A dilation balloon is than positioned and inflated within the subintimal layer to create a flap and corresponding pocket/sinus in the vein, which than acts as a one-way monocuspid valve in the manner of a native venous valve. In a similar manner, methods of forming new bicuspid venous valves by subintimal dissections are also disclosed.

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patent: WO01/49357 (2001-07-01), None
Dalsing, Michael, “Prosthetic venous Valves” The Vein Book, Chapter 64, pp. 593-598, 2006.
Peruzzi et al., “A New Autologous Venous Valve by Intimal Flap” Minerva Cardioangiologica, vol. 51, No. 4, p. 395, Aug. 2003.
Maleti et al., “Neovalve Construction in Postthrombotic Syndrome” The Journal of vascular Surgery, vol. 43, No. 4, pp. 794-799.

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