Percutaneous administration of nitroglycerine

Details Percutaneous administration of nitroglycerine Percutaneous administration of nitroglycerine

1980-11-03

1982-03-30

Cassiapaglia, Jr., Frank

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424343, 260467, A61K 3121

Patent

active

043224334

ABSTRACT:
A preparation for percutaneous administration of nitroglycerine, said preparation comprising nitroglycerine incorporated in a cream base in an amount not less than about 0.05% by weight based on the total weight of the preparation. The composition may also contain other medicaments, the bioavailability of which is enhanced by the nitroglycerine. The action of the preparation against for example angina may be brought about by having an appropriate amount of nitroglycerine or as additional medicament another medicament active against angina. The preparation may contain an hydroxyalkylcellulose which may provide, in combination with a waxy component in the cream, for example a higher aliphatic alcohol, a prolonged release effect. The preparation has advantages particularly as regards bioavailability over prior uniphasic ointments.

REFERENCES:
patent: 3609102 (1971-09-01), Schlossman
Nitrol.RTM. Ointment, package insert, 10/77.
Lachman et al., "Theory and Practice of Industrial Pharmacy", 2nd ed. 1976, pp. 215-244.

Affiliated with

Also associated with

Rating

Percutaneous administration of nitroglycerine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Percutaneous administration of nitroglycerine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Percutaneous administration of nitroglycerine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-382575