Percutaneous administration of 3'-azide'-deoxythymidine

Details Percutaneous administration of 3'-azide'-deoxythymidine Percutaneous administration of 3'-azide'-deoxythymidine

1990-05-14

1993-09-28

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514947, A01N 4304

Patent

active

052486745

ABSTRACT:
A method of administering 3'-azide-3'-deoxythymidine (AZT) to an AIDS patient who is in need of treatment with AZT, comprising applying AZT to the skin of said patient together with an absorption promoting agent capable of assisting absorption of AZT through the skin into the blood stream of said patient; and a percutaneous composition comprising AZT as an effective Ingredient together with an absorption promoting agent in an amount effective for assisting percutaneous absorption of AZT.

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Seki, et al., "Percutaneous Absorption of Azidothymidine in Rats", International Journal of Pharmaceutics, 57 (1989), pp. 73-75.

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