Percutaneous absorption type preparation and process for prepari

Details Percutaneous absorption type preparation and process for prepari Percutaneous absorption type preparation and process for prepari

1984-12-31

1988-01-12

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514447, 514448, A61F 1300, A61F 1302, A61F 1503, A61L 970

Patent

active

047192267

ABSTRACT:
A percutaneous absorption type preparation and a process for preparing the same, where the preparation comprises a backing readily conformable to the skin or mucosa and substantially impermeable to a drug absorbed through the skin or mucosa, and an adhesive layer provided on a backing, where the adhesive layer comprises a polymer which is pressure-adhesive at room temperature and the drug present in the polymer, wherein the amount of the drug present in the adhesive layer is greater than its saturated solubility in the polymer is dispersed in the polymer in the form of recrystallized fine particles. The excess portion is again dissolved in the polymer when the drug is consumed as the result of absorption through the skin or mucosa. The drug is released continuously over a long period of time.

REFERENCES:
patent: 3598122 (1971-10-01), Zaffarone
patent: 3598123 (1971-10-01), Zaffarone
patent: 3632740 (1972-01-01), Robinson et al.

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