Percutaneous absorption type pharmaceutical preparation of isoso

Details Percutaneous absorption type pharmaceutical preparation of isoso Percutaneous absorption type pharmaceutical preparation of isoso

1982-01-08

1983-12-13

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

A61L 1503, A61F 1300, A61K 970

Patent

active

044204701

ABSTRACT:
A pharmaceutical preparation comprising a flexible backing and a base material provided thereon is described wherein the base material consists essentially of a polymer having a glass transition temperature of from -70.degree. C. to -10.degree. C. and exhibiting pressure-sensitivity at room temperature, and isosorbide dinitrate or pentaerythritol tetranitrate. This pharmaceutical preparation is applied to the skin, and permits the active ingredient to be absorbed through the skin into the body at a constant rate, and gradually over a long period of time.

REFERENCES:
patent: 3742951 (1973-07-01), Zaffaroni
patent: 3972995 (1976-08-01), Tsuk et al.
patent: 4291015 (1981-09-01), Keith et al.
patent: 4336243 (1982-06-01), Sanvordeker
Dasta et al., "Topical Nitroglycerin", pp. 29-35 American Pharmacy N322(2), Feb. 1982.
Nitto Electric Ind. K.K., (Jul. 1980) Japan 55-92314, Derwent 61118 C/35, Abstract Card.
Toyo Ink Mfg. K.K. (Feb. 1980), Japan 55-20726, Derwent 22580 C/13, Abstract Card.
Uchimura K., (Feb. 1977), Japan 52-18812, Derwent 21065Y/12, Abstract Card.

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