Percutaneous absorption type cerebral protective agent

Details Percutaneous absorption type cerebral protective agent Percutaneous absorption type cerebral protective agent

2003-11-12

2011-12-13

Anderson, James D (Department: 1629)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

Reexamination Certificate

active

08076368

ABSTRACT:
A percutaneous absorption type cerebral protective agent containing as an active ingredient, 0.1 to 30 percent by mass of 3-methyl-1-phenyl-2-pyrazolin-5-one represented by the following formula:or a medically acceptable salt thereof in a base; a use of the compound as an active ingredient for the manufacture of a percutaneous absorption type pharmaceutical composition for protecting brain; and a method of protecting brain comprising administering to a patient the pharmaceutical composition as an active ingredient.

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Masahiko Tanaka, “Pharmacological and Clinical Profile of the Free Radical Scavenger Edaravone as a Neuroprotective Agent”, Abstract from Folia Pharmacologica Japonica, vol. 119 (2002), No. 5, 301-308.

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