Percutaneous absorption preparation

Details Percutaneous absorption preparation Percutaneous absorption preparation

1995-11-07

1997-07-22

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424447, 514946, 514947, A01N 2902, A61K 31035, A61L 1516, A61F 1302

Patent

active

056501650

ABSTRACT:
This invention provides a percutaneous absorption preparation for use in the percutaneous administration of drugs for percutaneous absorption into the living body for the purpose of preventing or treating various diseases, which has excellent adhesion to the skin and does not cause pain and damage to corneum when peeled off. Its pressure-sensitive adhesive layer contains an acrylic copolymer comprising a (meth)acrylic acid alkyl ester and a functional monomer as essential components, a fatty acid ester having a specified number of carbon atoms, a monoglyceride having a specified number of carbon atoms and a drug for percutaneous absorption, and the pressure-sensitive adhesive layer is crosslinked. Since its skin adhesive property is improved by the inclusion of the monoglyceride, release of the drug from the preparation is improved and the area of the preparation can be miniaturized.

REFERENCES:
patent: 3797494 (1994-03-01), Zaffaroni
patent: 5128124 (1992-07-01), Fankhauser et al.
patent: 5242951 (1993-09-01), Akemi et al.
patent: 5298258 (1994-03-01), Akemi et al.
patent: B13598122 (1982-11-01), Zaffaroni
Chemical Abstracts, vol. 112, No. 16, Apr. 16, 1990.

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