Percutaneous absorption preparation

Details Percutaneous absorption preparation Percutaneous absorption preparation

1997-03-07

1999-03-16

Brouillette, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424449, 424489, A61F 1302

Patent

active

058826750

ABSTRACT:
The present invention provides a percutaneous absorption preparation which has excellent pressure-sensitive adhesive characteristics and exerts excellent percutaneous absorption property. A crosslinking agent is added to a solution of an acrylic copolymer prepared by copolymerizing a (meth)acrylic acid alkyl ester with a functional monomer, and the acrylic copolymer is partially crosslinked. A composition containing the crosslinked acrylic copolymer is pulverized to prepare a pressure-sensitive adhesive solution comprised of the acrylic copolymer containing crosslinked acrylic copolymer particles. Thereafter, a drug for percutaneous absorption use, a percutaneous penetration enhancer are added to the pressure-sensitive adhesive solution, thereby producing the percutaneous absorption preparation.

REFERENCES:
patent: 3598123 (1971-08-01), Zaffaroni
patent: 4889721 (1989-12-01), Ueda
patent: 5028435 (1991-07-01), Katz
patent: 5077055 (1991-12-01), Mueller et al.
patent: 5556635 (1996-09-01), Istin
patent: 5582836 (1996-12-01), Carli

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