Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-11-07
2006-11-07
O'Sullivan, Peter (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S241000, C514S247000, C514S248000, C514S255060, C514S266100, C514S301000, C514S307000, C544S216000, C544S224000, C544S235000, C544S237000, C544S256000, C544S283000, C544S355000, C544S406000, C546S114000, C546S116000
Reexamination Certificate
active
07132418
ABSTRACT:
The present invention relates to a series of peptidyl heterocyclic ketones which are inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders. More particularly, these compounds are potent and selective inhibitors of tryptase and are therefore effective for the prevention and treatment of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis.
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Costanzo Michael J.
Maryanoef Bruce E.
Yabut Stephen C.
O'Sullivan Peter
Ortho-McNeil Pharmaceutical , Inc.
Woodrow Hal Brent
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