Peptidyl aminodiol renin inhibitors

Details Peptidyl aminodiol renin inhibitors Peptidyl aminodiol renin inhibitors

1990-06-29

1991-11-05

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 530331, 530332, 544162, 546141, 546146, 540451, 540476, 540523, 540593, 548225, 548344, 548537, 564153, 564157, A61K 3702, C07K 508

Patent

active

050632086

ABSTRACT:
A renin inhibiting compound having an aminodiol functional group is useful for treating hypertension, congestive heart failure and glaucoma and inhibits retroviral protease.

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Bolis et al., J. Med. Chem. 1987, 30(10), pp. 1729-1737.
Haber et al., J. Cardiovasc. Pharmacol., 1987, 10(Supp. 7), pp. S54-S58.

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