Peptidomimetic agents from dextrorotatory amino acids as...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S017800, C514S021700, C514S021800, C530S329000

Reexamination Certificate

active

07915220

ABSTRACT:
A peptidomimetic agent from dextrorotatory amino acids includes vGek with Dval-gly-Dglu-Dlys as a central D-amino acid sequence, whereby gly is equal to D-glycine, which is equal to L-glycine. Pharmaceutical agents for use in the treatment of neurodegenerative diseases, in particular Alzheimer's disease, Parkinson's disease, Lewy Body dementia, Creutzfeldt-Jakob disease, as well as Huntington's Chorea disease, multi-system atrophy as well as disorders similar to these neurodegenerative diseases that contain at least one peptidomimetic agent from dextrorotatory amino acids are also included.

REFERENCES:
patent: 2005/0287565 (2005-12-01), Merchiers et al.
patent: 2006/0036073 (2006-02-01), Windisch
patent: 2009/0286745 (2009-11-01), Zurdo et al.
patent: 03/082906 (2003-10-01), None
patent: WO 2005/023858 (2005-03-01), None
Fischer 2003 (Current Protein and Peptide Science 4:339-356).
Taylor et al. 2000 Journal of Pharmacology and Experimental Therapeutics 295:190-194.

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