Peptidoglycan recognition proteins and their production

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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530855, 530858, C07K 1400

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active

06034217&

ABSTRACT:
A gene coding for a peptidoglysan recognition peptide (PGRP) is cloned, a recombinant vector into which said gene is introduced is obtained, and a transformant transformed with said recombinant vector is cultivated, thereby producing the PGRP in large amounts at high purity.

REFERENCES:
patent: 4970152 (1990-11-01), Ashida et al.
patent: 5276269 (1994-01-01), Raikhel et al.
Bowie et al. Deciphering the message in protein sequences: tolerance to amino acid substitutions. Science, (Mar. 16, 1990) 247 (4948) 1306-10.
"Purification of a Peptidoglycan Recognition Protein From Hemolymph of the Silkworm, Bombyx mori," Journal of Biological Chemistry, vol. 271, No. 23, Jun. 7, 1996, pp. 13854-13860.

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