Peptides with β1 integrin subunit dependent cell...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 6 to 7 amino acid residues in defined sequence

Reexamination Certificate

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C514S015800, C514S016700, C514S017400, C514S018700, C530S327000, C530S328000

Reexamination Certificate

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06849712

ABSTRACT:
Peptides capable of modulating β1 integrin subunit dependent cell adhesion which includes a C-terminal aromatic amino acid residue and an amino acid residue having a lipophilic alkyl side chain as the penultimate C-terminal residue are provided. These “LipAr” C-terminated peptides are typically capable of modulating the β1 integrin subunit dependent adhesion of cells, such as Ramos cells.

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