Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2004-07-05
2010-02-23
Allen, Marianne P (Department: 1647)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S015800, C530S326000, C530S327000, C530S328000
Reexamination Certificate
active
07666841
ABSTRACT:
The described peptides possess the capacity to bind to Transforming Growth Factor TGF-β1 (TGF-β1), and are potential inhibitors of the biological activity of TGF-β1 through direct binding to this cytokine. These peptides can be used in the treatment of diseases or pathological alterations based on excessive or deregulated TGF-β1 expression.
REFERENCES:
patent: 2146552 (2000-08-01), None
patent: 8151396 (1996-06-01), None
patent: 0024782 (2000-05-01), None
Ishikawa, S. et al., “GD1α-replica peptides functionally mimic GD1α, an adhesion molecule of metastatic tumor cells, and suppress the tumor metastasis,” FEBS Letters, 1998, vol. 441, pp. 20-24.
Dotor De Las Herrerias et al., “International Search Report,” Oct. 8, 2004.
Borras Cuesta Francisco
Dotor De Las Herrerías Javier
Lasarte Sagastibelza Juan José
Lopez Vazquez Ana Belen
Prieto Valtuena Jesus
Allen Marianne P
Fuierer Tristan A.
Moore & Van Allen PLLC
Proyecto de Biomedicina Cima, S.L.
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