Peptides with pharmaceutical activity

Details Peptides with pharmaceutical activity Peptides with pharmaceutical activity

1989-03-15

1992-09-08

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514 18, 514 19, 530331, 564165, C07C23325

Patent

active

051458721

ABSTRACT:
Compounds of the formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and n have the meanings reported in the specification, processes for their preparation and pharmaceutical compositions containing them as active ingredient are described.
The compounds of formula I are inhibitor of enzymatic systems and they are useful in pharmaceutical field.

REFERENCES:
patent: 4029547 (1977-06-01), Umezawa et al.
patent: 4052449 (1977-10-01), Umezawa et al.
patent: 4395402 (1983-07-01), Umezawa et al.
patent: 4599325 (1986-07-01), Hansen et al.
patent: 4883808 (1989-11-01), Fodor et al.
patent: 4894392 (1990-01-01), Durette et al.
patent: 4900547 (1990-02-01), Levy et al.
patent: 4933179 (1990-06-01), Allison et al.
patent: 4942154 (1990-07-01), Durette et al.
Aoyagi et al., J. Appl. Biochem. 1984, vol. 6, pp. 212-221.
Poulson et al., ed. Organic Chemistry, 1980, pp. 1025-1031.
Talmadge et al., 13th Internatl. Congress of Chemotherapy, 1983, pp. 203/19-203/35.
Journal of Medicinal Chemistry, vol. 20, No. 4, Apr. 1977.

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