Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1987-08-24
1989-08-15
Phillips, Delbert R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530325, 530326, 530327, 530328, 530329, 530330, 530331, 530403, 435 7, 424 88, 424 89, C07K 706, C07K 708, C07K 710, A61K 3912
Patent
active
048576344
ABSTRACT:
A synthetic peptide, suitable for use in vaccination against or diagnosis of a disease caused by an enterovirus and especially by a poliovirus, is the peptide coded for by codons 286-290 in the RNA sequence coding for the structural capsid protein VP1 of poliovirus type 3 Sabin strain or by equivalent codons of another enterovirus or is an antigenic equivalent thereof, the numbers of the codons being counted from the 5'-terminus of the nucleotide sequence coding for the VP1 capsid protein.
REFERENCES:
patent: 4544500 (1985-10-01), Bittle et al.
patent: 4554101 (1985-11-01), Hopp
patent: 4694071 (1987-09-01), Almond et al.
Kitamura et al, Nature, vol. 291, pp. 547-553 (1981).
Evans et al, Nature, vol. 304, pp. 459-462 (1983).
Fricks et al, Journal of Virology, vol. 54, No. 3, pp. 856-859 (1985).
Minor et al, Chem. Abstr., vol. 105, No. 75533w (1986).
Minor et al., Applied Virology, pp. 31-49 (1984).
Minor et al., Review of Infectious Diseases, vol. 6, Supp. 2, pp. S516-S518 (1984).
Stanway et al., European Journal of Biochemistry, vol. 135, pp. 529-533 (1983).
Stanway et al., J. Virol., pp. 1187-1190 (3/1986).
J. Mol. Biol (1984), 174, pp. 561-585, "Complete Nucleotide Sequences of All Three Poliovirus Serotype Genomes", Toyoda et al.
"Poliomyelitis-Epidemiology, Molecular Biology and Immunology", P. D. Minor et al, Nature, vol. 299, Sep. 9, 1982, pp. 109-110.
"Primary Structure, Gene Organization and Polypeptide Expression of Poliovirus RNA", Kitamura et al, Mature, vol. 291, Jun. 18, 1981, pp. 547-553.
"Complete Nucleotide Sequence of the Attenuated Poliovirus Sabin 1 Strain Genome", A. Nomoto et al, Proc. Natl. Acad. Sci. USA, vol. 79, Oct. 1982, pp. 5793-5797.
"Location and Primary Structure of a Major Antigenic Site for Poliovirus Neutralization", P. D. Minor et al, Nature, vol. 301, Feb. 24, 1983, 674-679.
"Poliovirus Type 3-Molecular Cloning of the Genome and Nucleotide Sequence of the Region Encoding the Protease and Polymerase Proteins", A. J. Cann et al, Nuc. Acid Res., vol. 11, No. 5, 1983, pp. 1267-1281.
"Functional Basis of Poliovirus Neutralization Determined with Monospecific Neutralizing Antibodies", E. A. Emini et al., J. Virol., vol. 46, No. 2, May 1983, pp. 466-474.
"Critical Role of an Eight-Amino Acid Sequence or VP1 in Neutralization of Poliovirus Type 3", D. M. A. Evans et al, Nature, vol. 304, Aug. 4, 1983, pp. 459-462.
"Neutralizing Site of Poliovirus", F. Brown, Nature, vol. 304, Aug. 4, 1983, pp. 395-396.
"Priming For and Induction of Anti-Poliovirus Neutralizing Antibodies by Synthetic Peptides", E. A. Emini et al, Nature, vol. 304, Aug. 25, 1983, pp. 699-703.
"Will Peptides Make Vaccines?", P. Newmark, Nature, vol. 304, Sep. 1, 1983.
"Location and Sequence of a Critical Antigenic Site on VP1 of Poliovirus Type 3 and Its Relevance to the Development of Novel Vaccines Against Poliomyelitis", P. D. Minor et al, Chemical Abstracts, vol. 102, 1985, p. 454, 219283c.
"Prediction of Protein Antigenic Determinants from Amino Acid Sequences", Hopp and Woods, Proc. Natl. Acad. Sci, USA, vol. 78, No. 6, pp. 3824-3828, Jun. 1981.
"Monoclonal Antibodies Specific for the Sabin Vaccine Strain of Poliovirus", Ferguson et al, Lancet II, 1982, pp. 122--124.
"Neutralization Epitopes on Poliovirus Type 3 Particles: An Analysis Using Monoclonal Antibodies", J. Gen. Virol., 65, 1984, pp. 197-201, Ferguson et al.
"Trypsin Sensitivity of the Sabin Strain of Type 1 Poliovirus: Cleavage Sites in Virions and Related Particles", Fricks et al., J. Virol., Jun. 1985, pp. 856-859.
"Peptide-Induced Neutralizing Antibodies to Poliovirus", Jameson et al, Vaccines 85, Cold Spring Harbor Laboratory, 1985, pp. 191-198.
"Three-Dimensional Structure of Poliovirus at 2.9 .ANG. Resolution", Hogle et al, Science, 229, Sep. 27, 1985, 1358-1365.
"Antigenic Variation and Resistance to Neutralization in Poliovirus Type 1", Diamond et al., Science, 229, Sep. 13, 1985, pp. 1909-1093.
"Identification of a New Neutralization Antigenic Site on Poliovirus Coat Protein VP2", Emini et al, J. Virol., vol. 52, No. 2, 1984, 719-721.
"Induction by Synthetic Peptides of Broadly Reactive, Type-Specific Neutralizing Antibody to Poliovirus Type 3", Ferguson et al, Virol. 143, 1985, pp. 505-515.
"Principal and Subsidiary Antigenic Sites of VP1 Involved in the Neutralization of Poliovirus Type 3", P. D. Minor et al, J. Gen. Virol., 66, 1985, pp. 1159-1165.
"Antigenic Structure of Polioviruses of Serotypes 1, 2 and 3", Philip D. Minor et al, J. Gen. Virol., 67, 1986, pp. 1283-1291.
Almond Jeffrey W.
Evans David M. A.
Ferguson Morag
Minor Philip D.
Schild Geoffrey C.
Chan Christina
National Research Development Corporation
Phillips Delbert R.
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