Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2001-08-16
2008-10-14
Jiang, Dong (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S387300, C435S069700
Reexamination Certificate
active
07435793
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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Klein et al.,Selection for genes encoding secreted proteins and receptors, Proc. Natl. Acad. Sci. USA, vol. 93, pp. 7108-7113 (Jul. 1996).
Hu et al.,AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity, The Journal of Biological Chemistry, vol. 271, No. 18, Issue of May 3, pp. 10697-10703 (1996).
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Database search, Locus list: hum (349, 801 seqs, 66, 964, 548 aa), Mon Jan. 7 16:12:38 2002 [BLASTP 2.2.1 [Jul. 12, 2001], NCBI].
Database search, Locus list: hum—est (1, 803, 435 seqs, 6, 559, 376, 613 bp), Tue Jan. 8 09:15:03 [BLASTN 2.2.1 [Jul. 12, 2001], NCBI].
Tashiro, et al. “Signal Sequence Trap: A Cloning Strategy for Secreted Proteins and Type I Membrane Proteins.”Science. 26: 600-603 (Jul. 30, 1993).
Desnoyers Luc
Goddard Audrey
Godowski Paul J.
Gurney Austin L.
Wood William I.
Barnes Elizabeth M.
Genentech Inc.
Jiang Dong
Knobbe Martens Olson & Bear
Kresnak Mark T.
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