Peptides that bind to the erythropoietin receptor

Details Peptides that bind to the erythropoietin receptor Peptides that bind to the erythropoietin receptor

1997-03-28

1999-11-16

Kemmerer, Elizabeth

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

530323, 530324, 530325, 530326, 530327, 530328, C07K 704, C07K 706, C07K 708, C07K 1400

Patent

active

059860472

ABSTRACT:
Peptides of 10 to 40 or more amino acid residues in length and having the sequence X3X4X5GPX6TWX7X8 (SEQ ID NO:252) where each amino acid is indicated by standard one letter abbreviation; X3 is C; X4 is R, H, L, or W; X.sub.5 is M, F, or I; X6 is independently selected from any one of the 20 genetically coded L-amino acids; X7 is D, E, I, L, or V; and X8 is C, which bind and activate the erythropoietin receptor (EPO-R) or otherwise act as an EPO agonist, and methods for their use.

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