Peptides retroviral protease inhibitors comprising 2-amino-2-met

Details Peptides retroviral protease inhibitors comprising 2-amino-2-met Peptides retroviral protease inhibitors comprising 2-amino-2-met

1991-01-10

1992-09-08

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

4 to 5 amino acid residues in defined sequence

530331, C07K 504, C07K 506, A61K 3764, A61K 3702

Patent

active

051459515

ABSTRACT:
Antiviral peptides of the formula ##STR1## in which W is an amino protecting group,

REFERENCES:
Methods In Enzymology, vol. XXXIV, "Affinity Techniques, Enzyme Purification: Part B", Bovine Trypsin and Thrombin, Hixson, Jr. and A. H. Nishikawa, pp. 440-448, Academic Press, 1974.
Methods In Enzymology, vol. XXXIV, "Affinity Techniques, Enzyme Purification: Part B", Chymotrypsin(s), Tomlinson and Viswanatha, pp. 415-420, Academic Press 1974.
Affinity Chromatography, Biospecific Sorption; Affinity Chromatography of Chymotrypsin on Soybean Trypsin Inhibitor Sepharose: Applications in Genetics and Nuclide Labelling, Gabel, Kasche, Amneus and Lundqvist, pp. 99-102, Pergamon Press, 1977.
Applied Microbiology and Biotechnolgoy, Springer-Verlag 1979, Biotechnol. 6.; p. 195 (1979); "Recovery of Free Enzymes from Product Liquors by Bio-Affinity Adsorption: Trypsin Binding by Immobilised Soybean Inhibitor", Halling and Dunnill.
The Journal of Biological Chemistry, vol. 255, No. 15, Aug. 10, 1980 p. 7089, "Human Red Cell Purine Nucleoside Phosphorylase, Purification By Biospecific Affinity Chromatography and Physical Properties", Osborne, Mar. 17, 1980.
Hoppe-Scyler's Z. Physiol. Chem., vol. 361, p. 543, Apr. 1980, "Purification of Human and Bovine Alkaline Phosphatases by Affinity Chromatography", Mossner, Boll and Pfleiderer.
Analytical Biochemistry, vol. 107, p. 341, (1980), "Affinity Chromatographic Sorting of Carboxypeptidase A and its Chemically Modified Derivatives", Cueni, Bazzone, Riordan & Vallee, Mar. 31, 1980.
Hoppe-Seyler's Z. Physiol. Chem., vol. 359, p. 1019, Aug. 1978, "Affinity Chromatography of Bovine Bran .beta.-Hexosaminidases with Substrate as Affinity Ligand", Lisman and Overdijk, May 1978.
Biochem. J. (1978), vol. 175, p. 125, "Purification of the Hexokinases by Affinity Chromatography on Sepharose-N-Aminoacylglucosamine Derivatives", Wright, Warsy, Holroyde and Trayer, Feb. 1978.
Archives of Biochemistry and Biophysics, vol. 198, No. 2, Dec. 1979, p. 533, "Quantitative Affinity Chromatography of .alpha.-Chymotrypsin", Dunn and Gilbert, Aug. 10, 1979.
T. J. McQuade et al., Science 247:454-456, 26 Jan. 1990.
A. G. Tomasselli et al., Biochemistry 29: 264-269, 1990.

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