Peptides representing permutations of the mastoparan sequence

Details Peptides representing permutations of the mastoparan sequence Peptides representing permutations of the mastoparan sequence

1992-10-16

1996-05-21

Chan, Christina Y.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

11 to 14 amino acid residues in defined sequence

530326, C07K 708

Patent

active

055191169

ABSTRACT:
New peptides representing permutations of the mastoparan sequence are described. The peptides may be of pharmaceutical interest in counteracting pathologies due to alterations in the interaction between membrane receptors and G-proteins.

REFERENCES:
Communication and European Search Report in Corresponding European Patent Application No. 92203174.5.
Ken Nagashima et al, "Role Of Lysine Residue At 7th Position Of WASP Chemotactic Peptides," Biochemical and Biophysical Research Communications, vol. 168, No. 2, pp. 844-849 (Apr. 30, 1990).
Yuko Hirai et al, "A New Mast Cell Degranulating Peptide `Mastoparan` In The Venom of Vespula Lewisii," Chem. Pharm. Bull., vol. 27, No. 8, pp. 1942-1944 (1979).
Cristina Oppi et al, "Attenuation of Gtpase Activity Of Recombinant G.sub.o .alpha. By Peptides Representing Sequence Permutations of Mastoparan," Proc. Natl. Acad. Sci. USA, vol. 89, No. 17, pp. 8268-8272 (Sep. 1992).
Goate, A., Chartier-Harlin, M.-C., Mullan, M. Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L., Mant, R., Newton, P., Rooke, K., Roques, P., Talbot, C., Pericke-Vance, M., Roses, A., Williamson, R., Rossor, M., Owen, M. and Hardy, J., Nature, 349 (1991), 704-706.
Higashijima, T., Usu, S., Nakajima, T. and Ross, E. M., J. Biol. Chem., 263 (1988), 6401-6494.
Oppi, C., Wagner, T., Crisari, A., Camerini, B. and Tocchini Valentini, G. P., Proc. Natl. Acad. Sci. USA, 89 (1992), 8268-8272.
Higashijima, I., Burnier, J. and Ross, E. M. J. Biol. Chem., 265 (1990), 14176-14186.
Cheung, A. H., Huang, R. -R. C., Graziano, M. P. and Strader, C. D., FEBS Lett., 279 (1991), 277-280.
Okamoto, T., Murayama, Y., Hayashi, Y., Inagaki, M., Ogata, E. and Nishimoto, I., Cell, 67 (1991), 723-730.
Bauer, P. H., Mueller, S., Puzicha, M., Pippig, S., Obermaier, B., Heimreich, E. J. M. and Lohse, M. J., Nature, 358 (1992), 73-76.
Selkoe, D. J., Cell, , 58 (1989), 611-612.
Dyrks, T., Weidemann, A., Multhaup, G., Salbaum, J. M., Lemaire, H. -G., Kang, J., Mueller-Hill, B., Masters, C. L., and Beyreuther, K., Embo J., 7 (1988), 949-957.
Nishimoto, I., Okamoto, T., Matsuura, Y., Takahashi, S., Okamoto, T., Murayama, Y. and Ogata, L., Nature, 362 (1993), 75-79.
Oppi, C. et al; PNAS 89, 8268-8272, 1992.
Higashijima, T. et al.; JBC 265, 14176-14186, 1990.
Argiolas, A et al, JBC 259, 10106-10111, 1984.

Affiliated with

Also associated with

Rating

Peptides representing permutations of the mastoparan sequence does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptides representing permutations of the mastoparan sequence, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides representing permutations of the mastoparan sequence will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2038965