Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-07
1996-09-17
Parr, Margaret
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 732, 435 734, 530300, 530324, 530327, 530329, 514 2, G01N 3353, G01N 33554, G01N 33569, C07K 700
Patent
active
055567576
ABSTRACT:
Peptides comprising a Meningitis Related Homologous Antigenic Sequence (MRHAS) are provided. The MRHAS is found in meningitis-causing organisms and chemokines involved in cell chemotaxis. The peptides are useful as antigens and vaccines for detection, diagnosis and treatment of meningitis.
REFERENCES:
Roos "Chapter 16", Sheld, et al. eds., Infections of the CNS :335 (1991).
Herrmann "Rubella Virus", Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections :725 (1979).
Spalding "In Hot Pursuit of an HIV Vaccine", Biotech 10:24-29 (1992).
Green et al. EMBL Bank (1992).
Griffiss et al. "Vaccines Against Encapsulated Bacteria: A Global Agenda", Rev. Infec. Dis . 9:176-188 (1987).
Yoshimura et al. "Human monocyte chemoattractant protein-1 (MCP-1)", FEBS Letters 244:487-493 (1989).
Terry et al. "Localization of the rubella E1 epitopes", Arch. Virol . 98:189-197 (1988).
Connolly et al. "Carotid Artery Thrombosis, Encephalitis, Myelitis and Optic Neuritis Associated with Rubella Virus Infections", Brain 98:583-594 (1975).
Pope and "Van Alstyne Evidence for Restricted Replication of rubella Virus in Rat Glial Cells in Culture", Virology 113:776-780 (1981).
Van Alstyne and Paty "The Effect of Dibutyryl Cyclic AMP on Restricted Replication of Rubella Virus in Rat Glial Cells in Culture", Virology 124:173-180 (1983).
Voller and Bidwell "A Simple Method for Detecting Antibodies to Rubella", Br. J. Exp. Path . 56:338-339 (1975).
Parkman and Meyer et al. "Attenuated Rubella Virus", The New England Journal of Medicine 275:569-580 (1966).
Stephens et al. "Equine Infectious Anemia Virus gag and pol Genes: Relatedness to the Visna and AIDS Virus", Science 231:589-594 (1986).
Ho et al. "Primary Human T-Lymphotropic Virus Type III Infection", Annals of Internal Medicine 103:880-883 (1985).
Muesing et al. "Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus", Nature 313:450-458 (1985).
Fraser et al. "Bacterial Meningitis in Bernilillo County, New Mexico: A Comparison with Three Other American Populations", Am. J. of Epidemology 100:29-34 (1974).
Yother and Briles "Structural Properties and Evolutionary Relationships of PspA, a Surface Protein of Streptococcus pneumoniae as Revealed by Sequence Analysis", J. of Bacteriology 174:601-609 (1992).
Tunkel et al. "Bacterial Meningitis: Recent Advances in Pathophysiology and Treatment", Annals of Internal Medicine 112:610-623 (1990).
Stern and Meyer "Common mechanism controlling phase and antigenic variation in pathogenic neisseriae", Molecular Microbiology 1:5-12 (1987).
Goebel et al. "Studies on the Pathogenicity of Listeria monocytogenes", Infection 19:S195-197 (1991).
Michel and Cossart "Physical Map of the monocytogenes Cromosome", Journal of Bacteriology 174:7098-7103 (1992).
Kohler et al. "The Gene Coding for Protein p60 of Listeria monocytogenes and Its Use as a Specific Probe for Listeria monocytogenes", Infection and Immunity 58:1943-1950 (1990).
Cordy "Pathomorphiology and Pathogenesis of Bacterial Meningoventriculitis of Neonatal Ungulates", Vet. Pathol. 21:587-591 (1984).
Robinson et al. "Complete amino acid sequence of a human monocyte chemoattractant, a putative mediator of cellular immune reactions", Proc. Natl. Acad. Sci. USA 86:1850-1854 (1989).
Michiel et al. "Chemokines: The Missing Link", Bio/technology 11:739 (1993).
Rollins et al. "The Human Homolog of the JE Gene Encodes a Monocyte Secretory Protein", Molecular and Cellular Biology 9:4687-4695 (1989).
Van Damme et al. "Structural and Functional Identification of Two Human, Tumor-derived Monocyte Chemotactic Proteins (MCP-2 and MCP-3) Belonging to the Chemokine Family", J. Exp. Med. 176:59-64 (1992).
Green et al. "The e (P4) Outer Membrane Protein of Haemophilus influenzae: Biologic Activity of Anti-e Serum and Cloning and Sequencing of the Structural Gene, " Infection and Immunology 59:3191-3198 (1991).
Waldmann, T. A. Science 252:1657-1662 (1991).
Waxham et al. Virology 143:153-165 (1985).
Alstyne Diane V.
Sharma Lawrence R.
Insight Biotek, Inc.
Loring Susan A.
Parr Margaret
LandOfFree
Peptides representing epitopic sites for bacterial and viral men does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptides representing epitopic sites for bacterial and viral men, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides representing epitopic sites for bacterial and viral men will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-412493