Peptides related to human immunodeficiency virus II (HIV-2)

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

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530325, 530326, 530387, 930221, 930DIG811, 930DIG821, C07K 1504, C07K 708, C07K 710

Patent

active

050514962

ABSTRACT:
A method for diagnosing an HIV-2 (LAV-II) infection and a kit containing reagents for the same is disclosed. These reagents include cDNA probes which are capable of hybridizing to at least a portion of the genome of HIV-2. In one embodiment, the DNA probes are capable of hybridizing to the entire genome of HIV-2. These reagents also include polypeptides encoded by some of these DNA sequences.

REFERENCES:
Kanki et al, "Serologic Identification and Characterization of a Macaque T-Lymphotropic Retrovirus Closely Related to HTLV-III", Science 228 (1985), 1199-1201.
Daniel et al, "Isolation of T-Cell Tropic HTLV-III-Like Retrovirus from Macaques", Science 228 (1985) 1201-1204.
Clavel et al, "Isolation of a New Human Retrovirus from West African Patients with AIDS", Science 233 (1986) 343-346.
Clavel et al, "Molecular Cloning and Polymorphism of the Human Immune Deficiency Virus Type 2", Nature 324 (1986) 691-695.

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