Peptides of CaV2.2 that inhibit pain

Details Peptides of CaV2.2 that inhibit pain Peptides of CaV2.2 that inhibit pain

2008-08-12

2010-11-09

Kosar, Andrew D (Department: 1654)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C506S016000, C506S017000, C536S023400

Reexamination Certificate

active

07829688

ABSTRACT:
The present invention relates to peptides of CaV2.2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2.2. and is believed to inhibit the interaction of CaV2.2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.

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