Peptides involved in the pathogenesis of HIV infection

Details Peptides involved in the pathogenesis of HIV infection Peptides involved in the pathogenesis of HIV infection

1989-10-30

1991-05-21

Doll, John

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

530327, 424 88, 424 89, 514 13, 514 14, C07K 708, A61K 3702, A61K 3912

Patent

active

050176889

ABSTRACT:
This invention relates to peptides involved in the pathogenesis of human immunodeficiency virus ("HIV"). More particularly, this invention relates to peptides from the env region of the HIV genome and the use of such peptides in methods and compositions for preventing, treating, or detecting acquired immune deficiency syndrome ("AIDS") infection.

REFERENCES:
patent: 4520113 (1985-05-01), Gallo et al.
patent: 4591552 (1986-05-01), Newrath
patent: 4629783 (1986-12-01), Cosand
N. T. Chang et al., "An HTLV-III Peptide Produced by Recombinant DNA is Immunoreactive with Sera from Patients with AIDS", Nature, 315, pp. 151-54 (1985) [Chang et al. I].
N. T. Chang et al., "Expression in Escherichia coli of Open Reading Frame Gene Segments of HTLV-III", Science, 228, pp. 93-96 (1985) [Chang et al. II].
T. C. Chanh et al., "Induction of Anti-HIV Neutralizing Antibodies by Synthetic Peptides", EMBO J., 5, pp. 3065-+71 (1986).
R. Crowl et al., "HTLV-III env Gene Products Synthesized in E. coli are Recognized by Antibodies Present in the Sera of AIDS Patients", Cell, 41, pp. 979-986 (Jul. 1986).
R. C. Kennedy et al., "Antiserum to a Synthetic Peptide Recognizes the HTLV-III Envelope Glycoprotein", Science, 231, pp. 1556-1559 (Mar. 28, 1986).
D. Pauletti et al., "Application of a Modified Computer Algorithm in Determining Potential Antigenic Determinants Associated with the AIDS Virus Glycoprotein", Analytical Biochemistry, 151, pp. 540-546.
L. Ratner et al., "Complete Nucleotide Sequence of the AIDS Virus, HTLV-III", Nature, 313, pp. 277-284 (Jan. 1985).
Fauci et al., Ann. Inst. Pasteur/Immunol. vol. 138, pp. 261-268 (1987).
Broder et al., The Lancet, pp. 627-630 (1985).
McClure et al., Current Topics in AIDS, vol. 1, Gottlieb et al. (Ed.) John Wiley & Sons, New York, pp. 95-117 (1987).
Fauci, Proc. Natl. Acad. Sci. USA vol. 83 pp. 9278-9283 (12/1986).
Chang et al., Bio/Technology vol. 3, pp. 905-909 (10/85).
Starcich et al., Cell, vol. 45 pp. 637-648, (6/6/86).

Affiliated with

Also associated with

Rating

Peptides involved in the pathogenesis of HIV infection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptides involved in the pathogenesis of HIV infection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides involved in the pathogenesis of HIV infection will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-239512