Peptides inhibiting the oncogenic action of p21 ras

Details Peptides inhibiting the oncogenic action of p21 ras Peptides inhibiting the oncogenic action of p21 ras

1995-09-21

1998-11-24

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 11, 514 14, 514 15, 514 16, 514 17, 514 18, 530317, 530326, 530327, 530328, 530329, 530330, 530331, A61K 3812, C07K 508

Patent

active

058406832

ABSTRACT:
The present invention provides peptides and cyclized peptides which inhibit the oncogenic and/or transforming activity of the p21 ras protein, pharmaceutical compositions containing at least one of the ras-inhibiting peptides, cyclized peptides and peptidomimetics, and methods for inhibiting the ras-mediated oncogenic and/or transformation process in mammalian cells or tissues.

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