Peptides having gonadoliberin activity and process for their man

Details Peptides having gonadoliberin activity and process for their man Peptides having gonadoliberin activity and process for their man

1977-04-20

1978-10-03

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125LH, A61K 3700, C07C10352

Patent

active

041184831

ABSTRACT:
A peptide with LH-RH-activity which is a LH-RH-peptide wherein Gly in 6-position is replaced by D-glutaminic-acid which may be N-substituted at the CO-NH.sub.2 moiety, wherein in 10-position Gly-NH.sub.2 may be replaced by a NH-alkyl or NH-cycloalkyl group and/or wherein the amino acids in 4-, 5-, 7- and/or 8-position may be replaced by other amino acids and a process for its manufacture.

REFERENCES:
patent: 4003884 (1977-01-01), Konig et al.
patent: 4024248 (1977-05-01), Konig et al.

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