Peptides having atrial natriuretic factor activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

514 11, 514 12, 530317, 530324, 530325, 530326, A61K 3702, C07K 710

Patent

active

052043282

ABSTRACT:
Atrial natriuretic factor analogs containing N-alkylated amino acids and showing enhanced potency and increased metabolic stability. These analogs have natriuretic, diuretic and vasorelaxant activity, making them suitable for treating congestive heart failure and renal hypertension.

REFERENCES:
Stephenson S. et al., Biochem. J., 243:183-187, 1987.
Baxter, J., et al., Biotechnology, 6:529-546, 1988.

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