Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-06-27
1998-11-17
Lukton, David
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 2, 514 11, 530300, 530317, 43525234, A61K 3812
Patent
active
058376852
ABSTRACT:
Peptide antimycotics, termed pseudomycins, display broad spectrum antibiotic activity, and in particular are highly effective, non-toxic antibiotics against fungal pathogens of human and animal disease. The peptide antimycotics (pseudomycins) may be used in the treatment of the fungal pathogen Candida albicans. Also disclosed is a method of purification and isolation, including characterization, of the pseudomycins.
REFERENCES:
patent: 5576298 (1996-11-01), Strobel et al.
Master's Thesis, Harrison, Leslie, Montana State University, pp. 1-61, Oct. , 1990.
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"Structure and Stereochemistry of Three Phytotoxins . . . ," Fukuchi, N., et al., J. Chem. Soc. Perkin Trans. 1 (1992), (9), 1149-57.
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"Pseudomycins, a family of novel peptides from Pseudomonas syringae possessing broad-spectrum antifungal activity", Harrison et al., Journal of Microbiology, pp. 2857-2865, 1991.
Harrison Leslie A.
Strobel Gary A.
Teplow David B.
Lukton David
Research and Development Institute Inc. at Montana State Univers
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