Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-09-15
1996-11-19
Weimar, Elizabeth C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 11, 530317, 530328, 43525234, A61K 3808
Patent
active
055762980
ABSTRACT:
Peptide antimycotics, termed pseudomycins, display broad spectrum antibiotic activity, and in particular are highly effective, non-toxic antibiotics against fungal pathogens of human and animal disease. The peptide antimycotics (pseudomycins) may be used in the treatment of the fungal pathogen Candida albicans. Also disclosed is a method of purification and isolation, including characterization, of the pseudomycins.
REFERENCES:
Harrison et al., "Pseudomycins, a family of novel peptides from Pseudomonas yringae possessing broad-spectrum antifungal activity", Journal of Mircobiology, pp. 2857-2865, 1991.
Harrison, Master's Thesis, pp. 1-61.
Grgwrina, Experientia 50, 130, 1994.
Ballio FEBS Lett 355, 96, 1994.
Ballio FEBS Lett 269, 377, 1990.
Segre, Phytotox & Plant Pathogen, 367; 1989.
Fukuchi Tet Lett 31, 1589, 1992.
Fukuchi, J Chem Soc Perk Trans I 1149-1157, 1992.
Fukuchi J Chem Soc Perk Trans I 875-880, 1992.
Harrison Leslie A.
Strobel Gary A.
Teplow David B.
Lukton David
Research and Development Institute, Inc. at Montana State Univer
Weimar Elizabeth C.
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