Peptides from pseudomonas syringae possessing broad-spectrum ant

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 11, 530317, 530328, 43525234, A61K 3808

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active

055762980

ABSTRACT:
Peptide antimycotics, termed pseudomycins, display broad spectrum antibiotic activity, and in particular are highly effective, non-toxic antibiotics against fungal pathogens of human and animal disease. The peptide antimycotics (pseudomycins) may be used in the treatment of the fungal pathogen Candida albicans. Also disclosed is a method of purification and isolation, including characterization, of the pseudomycins.

REFERENCES:
Harrison et al., "Pseudomycins, a family of novel peptides from Pseudomonas yringae possessing broad-spectrum antifungal activity", Journal of Mircobiology, pp. 2857-2865, 1991.
Harrison, Master's Thesis, pp. 1-61.
Grgwrina, Experientia 50, 130, 1994.
Ballio FEBS Lett 355, 96, 1994.
Ballio FEBS Lett 269, 377, 1990.
Segre, Phytotox & Plant Pathogen, 367; 1989.
Fukuchi Tet Lett 31, 1589, 1992.
Fukuchi, J Chem Soc Perk Trans I 1149-1157, 1992.
Fukuchi J Chem Soc Perk Trans I 875-880, 1992.

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