Peptides for use in wound treatment

Details Peptides for use in wound treatment Peptides for use in wound treatment

1998-01-15

2000-08-01

Tsang, Cecilia J.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

4 to 5 amino acid residues in defined sequence

530328, 530329, 514 15, 514 16, 514 17, A61K 3804, C07K 500

Patent

active

060968648

ABSTRACT:
The invention provides wound treatment compositions comprising from 10.sup.-6 % to 1.0% w/w of one or more peptides, wherein the peptides are from 3 to 30 amino acid residues long and comprise the sequence Gly-Pro-Ala. Preferably, the peptides comprise the sequence Gly-Pro-Ala-Gly, more preferably at the N-terminus. The peptides exhibit a chemotactic effect towards fibroblasts.

REFERENCES:
patent: 5235038 (1993-08-01), Blondelle et al.
patent: 5591711 (1997-01-01), Koyama et al.
WPI Abstract Accession No. 84-235498/38 & RO 0083934 A Radulescu et al. May, 5, 1984 (see abstract).
A.E. Postlethwaite et al. in Proceedings of National Academy of Science, vol. 75, pp. 871-875 (1978).
Sato, et al., Bull. Chen. Soc. Jpn. 1983, 56, 1657.

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